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Dr Conall Dennedy

mcd53@medschl.cam.ac.uk

+44 (0)1223 336786

 

Conall is a visiting fellow from Ireland, where he has just completed his PhD on the immuno-metabolic effects of innate immunity in metabolically unhealthy obesity. He is a trained clinician specialising in endocrinology under the Health Research Board of Ireland funded, National Academic SpR Fellowship programme. He completed his undergraduate training at National University of Ireland, completing a BSc in 1999 and MB, BAO, BCh in 2002. He completed his MRCPI in 2005 and was awarded an MD from NUI, Galway in Obstetrics entitled “The Beta-3 Adrenoreceptor Modulates Myometrial Relaxation in Humans without Adverse Vascular Relaxant Effects” in 2007. He will graduate with his PhD in 2013.

 

Conall’s main research and clinical interest lies in the area of obesity, particularly the interaction between obesity and the innate immune system, specifically monocytes, to modulate vascular risk. He also has an interest in population based research investigating the effects of gestational obesity and gestational weight gain.

 

Publications & Work:

 

1. Dennedy MC, Prado-Lopez S. Hanley S, Connaughton E, Slevin S, O’Shea D, Ceredig R, O’Brien T, Griffin M. (2013). A novel subset of intermediate monocytes is expanded in obesity and is associated with adverse metabolic risk. Submitted: 2013.

 

2. Dennedy MC, Dunne F. (2013). Macrosomia: Defining the Problem Worldwide. Lancet. 2013; Jan 3 Epub ahead of print. Abstract.

 

3. Dennedy MC, Avalos G, O’Reilly MW, O’Sullivan EP, Gaffney G, Dunne F. (2012). ATLANTIC-DIP: Raised maternal body mass index (BMI) adversely affects maternal and fetal outcomes in glucose tolerant women, classified using International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria. Journal of Clinical Endocrinology and Metabolism. 2012; 97: E608-12. Abstract.

 

4. O’Reilly M, Avalos G, Dennedy MC, O’Sullivan EP, Dunne F. (2011). ATLANTIC DIP: High prevalence of abnormal glucose tolerance postpartum is lower in women with prior gestational diabetes mellitus. European Journal of Endocrinology. 2011; 165: 953-9. Abstract.

 

5. O’Sullivan EP, Avalos G, O’Reilly M, Dennedy MC, Gaffney G, Dunne F. (2011). Atlantic Diabetes in Pregnancy (DIP): The prevalence and outcomes of gestational diabetes mellitus using new diagnostic criteria. Diabetologia. 2011; 10: 2150-4.

 

6. Dennedy MC, Dunne F. (2010). The maternal and fetal aspects of obesity and gestational diabetes on pregnancy outcome. Best Practice and Research Clinical Endocrinology and Metabolism. 2010; 24: 573-589. Abstract.

 

7. Houlihan DD, Dennedy MC, Morrison JJ. (2010). Effects of abnormal cannabidiol on human pregnant myometrium. Reproduction. 2010; 139: 783-8. Abstract.

 

8. Dennedy MC, Smith D, O’Shea D, McKenna TJ. (2010). Clinical Practice Update: Investigation of patients with atypical or severe hyperandrogenaemia, including androgen secreting ovarian teratoma. European Journal of Endocrinology. 2010; 162: 213-20. Abstract.

 

9. Muthusamy K, Smith SA, Dinneen SF, Dennedy MC. ACP Journal Club. Minimally invasive and conventional glucose monitoring did not differ for long-term glycaemic control in insulin-treated diabetics. (2009). Annals of Internal Medicine. 2009; 151: JC4-6, JC4-7. Abstract.

 

10. Houlihan DD, Dennedy MC, Ravikumar N, Morrison JJ. (2004). Antihypertensive therapy and the feto-placental circulation: effects on umbilical artery resistance. Journal of Perinatal Medicine. 2004; 32: 315-9. Abstract.

 

11. Dennedy MC, Friel AM, Houlihan DD, Broderick VB, Smith T, Morrison JJ. (2004). Cannabinoids and the human uterus during pregnancy. American Journal of Obstetrics and Gynecology. 2004; 190; 2-9. Abstract.

 

12. Potter SM, Dennedy MC, Morrison JJ. (2002). Corticosteroids and fetal vasculature: effects of hydrocortisone, dexamethasone and betamethasone on human umbilical artery. British Journal of Obstetrics and Gynaecology. 2002; 109: 1126-31. Abstract.

 

13. Dennedy MC, Houlihan DD, McMillan H, Morrison JJ. (2002). Beta-2 and beta-3 adrenoreceptor agonists: Human myometrial selectivity and effects on umbilical artery resistance. American Journal of Obstetrics and Gynecology. 2002; 187: 641-47. Abstract.

 

14. Houlihan DD, Dennedy MC, Morrison JJ. (2002). Polyamine effects on human myometrial contractility. American Journal of Obstetrics and Gynecology. 2002; 186: 778-83. Abstract.

 

15. Connor TJ, Dennedy MC, Harkin A, Kelly JP. Methylenedioxymethamphetamine-induced suppression of interleukin-1 beta and tumour necrosis factor-alpha is not mediated by serotonin. (2001). European Journal of Pharmacology. 2001; 418: 147-52. Abstract.

 

16. Dennedy MC, Friel AM, Gardeil F, Morrison JJ. (2000). Beta-3 versus beta-2 adrenergic agonists and preterm labour: in vitro uterine relaxation effects. British Journal of Obstetrics and Gynaecology. 2000; 108: 605-09. Abstract.