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Dr Jules Griffin

Lipid Profiling and Signalling

The interaction between being overweight and type 2 diabetes arises because fats become inappropriately stored in organs such as the liver, pancreas and skeletal muscle, reducing the body’s capacity to respond to the hormone insulin, an important signal which regulates the storage of nutrients. The lipid profiling and signalling (LPS) Group are using novel mass spectrometry and multivariate statistics to understand these processes. We have a range of studies that investigate the effects of over-nutrition, and in particular the role that high fat intake plays in inducing disease.