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Dr Ruth Loos

Professor and Program Director


Genetics of Obesity and Related Metabolic Traits Program

Charles R. Bronfman Institute for Personalized Medicine

Department of Preventive Medicine


One Gustave L. Levy Place

Box 1003

New York, NY 10029


Telephone: 212 – 241 – 5025

Fax: 212 – 849 – 2643


Research Interests

Ruth’s primary research interests focuses on the identification of genes and genetic loci contributing to the risk of obesity and related metabolic traits and on how lifestyle modifies these genetic effects. Ruth is a member of the GIANT (Genetic Investigation of ANTropometric Traits) consortium, with whom she identified a series of genetic variants unequivocally associated with obesity. She has also set up GWAS consortia for body fat percentage, for leptin levels, and also for resting heart rate. Besides gene-discovery, Ruth uses epidemiological methods to follow-up on established loci with the aim to elucidate the pathways through which they increase risk of metabolic disease. Furthermore, her work assesses the public health implications of the established loci by examining their predictive value and their interaction with lifestyle factors such as diet and physical activity.




Previous positions

Ruth obtained her PhD at the University of Leuven (Belgium) in 2001, after which she was a postdoctoral fellow at the Pennington Biomedical Research Center in Baton Rouge (LA, USA) in Dr Claude Bouchard’s Human Genetics laboratory. In July 2005, she joined the MRC Epidemiology Unit of the Institute of Metabolic Science in Cambridge (England) to become Group Leader of the Genetic Aetiology of Obesity Programme. Ruth joined the Mount Sinai School of Medicine in New York in December 2011, and remains an honorary member of the MRC Epidemiology Unit in Cambridge.