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Prof Toni Vidal-Puig, all publications

{pubmed_search=^((Vidal-Puig A[Author]) AND “2011”[Date – Publication] : “3000”[Date – Publication]) AND “0”[Date – Publication] : “3000”[Date – Publication]^}

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  1. Extracellular Vesicles: Novel Mediators of Cell Communication In Metabolic Disease.

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    Trends Endocrinol Metab. 2016 Oct 31. pii: S1043-2760(16)30128-X. doi: 10.1016/j.tem.2016.10.003. [Epub ahead of print]

    Huang-Doran I1, Zhang CY2, Vidal-Puig A3.

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    PMID: 27810172 DOI: 10.1016/j.tem.2016.10.003

  2. Metabolic gene expression profile in circulating mononuclear cells reflects obesity-associated metabolic inflexibility.

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    Nutr Metab (Lond). 2016 Oct 27;13:74. eCollection 2016.

    Baig S1, Parvaresh Rizi E2, Shabeer M1, Chhay V1, Mok SF3, Loh TP4, Magkos F5, Vidal-Puig A6, Tai ES7, Khoo CM7, Toh SA8.

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    PMID: 27800008 PMCID: PMC5081666 DOI: 10.1186/s12986-016-0135-5

  3. Stearoyl-CoA Desaturase 1 Is a Key Determinant of Membrane Lipid Composition in 3T3-L1 Adipocytes.

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    PLoS One. 2016 Sep 15;11(9):e0162047. doi: 10.1371/journal.pone.0162047. eCollection 2016.

    Rodriguez-Cuenca S1, Whyte L2, Hagen R1, Vidal-Puig A1,3, Fuller M2,4.

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    PMID: 27632198 PMCID: PMC5025088 DOI: 10.1371/journal.pone.0162047

  4. Assessment of plasma acylcarnitines before and after weight loss in obese subjects.

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    Arch Biochem Biophys. 2016 Sep 15;606:73-80. doi: 10.1016/j.abb.2016.07.013. Epub 2016 Jul 19.

    Schooneman MG1, Napolitano A2, Houten SM3, Ambler GK4, Murgatroyd PR5, Miller SR2, Hollak CE6, Tan CY4, Virtue S4, Vidal-Puig A4, Nunez DJ2, Soeters MR7.

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    PMID: 27444119 DOI: 10.1016/j.abb.2016.07.013

  5. Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness.

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    Nat Med. 2016 Jul;22(7):771-9. doi: 10.1038/nm.4115. Epub 2016 Jun 6.

    Morton NM1, Beltram J2, Carter RN1, Michailidou Z1, Gorjanc G2, McFadden C1, Barrios-Llerena ME1, Rodriguez-Cuenca S3, Gibbins MT1, Aird RE1, Moreno-Navarrete JM4,5,6, Munger SC7, Svenson KL7, Gastaldello A1, Ramage L1, Naredo G1, Zeyda M8, Wang ZV9, Howie AF10, Saari A11, Sipilä P12, Stulnig TM8, Gudnason V13, Kenyon CJ1, Seckl JR1, Walker BR1, Webster SP1, Dunbar DR1, Churchill GA7, Vidal-Puig A3,14, Fernandez-Real JM4,5,6, Emilsson V13,15, Horvat S2,16.

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    PMID: 27270587 DOI: 10.1038/nm.4115

  6. Mild cold effects on hunger, food intake, satiety and skin temperature in humans.

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    Endocr Connect. 2016 Mar;5(2):65-73. doi: 10.1530/EC-16-0004. Epub 2016 Feb 10.

    Langeveld M1, Tan CY1, Soeters MR2, Virtue S1, Ambler GK3, Watson LP4, Murgatroyd PR4, Chatterjee VK1, Vidal-Puig A1.

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    PMID: 26864459 PMCID: PMC5002965 DOI: 10.1530/EC-16-0004

  7. Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues.

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    Diabetologia. 2016 Jun;59(6):1075-88. doi: 10.1007/s00125-016-3933-4. Epub 2016 Apr 4.

    Pellegrinelli V1, Carobbio S2,3, Vidal-Puig A4,5.

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    PMID: 27039901 PMCID: PMC4861754 DOI: 10.1007/s00125-016-3933-4

  8. Erratum: Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance.

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    Sci Rep. 2016 Mar 30;6:23873. doi: 10.1038/srep23873.

    Tan CY, Virtue S, Murfitt S, Roberts LD, Phua YH, Dale M, Griffin JL, Tinahones F, Scherer PE, Vidal-Puig A.

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    PMID: 27027977 PMCID: PMC4813347 DOI: 10.1038/srep23873

  9. Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome.

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    PLoS Genet. 2016 Mar 10;12(3):e1005916. doi: 10.1371/journal.pgen.1005916. eCollection 2016.

    Van De Pette M1, Tunster SJ1, McNamara GI1, Shelkovnikova T1, Millership S2, Benson L3, Peirson S3, Christian M4, Vidal-Puig A5, John RM1.

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    PMID: 26963625 PMCID: PMC4786089 DOI: 10.1371/journal.pgen.1005916

  10. Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice.

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    Stress. 2016;19(2):214-24. doi: 10.3109/10253890.2016.1151491. Epub 2016 Mar 7.

    Sanghez V1,2, Cubuk C3, Sebastián-Leon P3, Carobbio S4, Dopazo J3, Vidal-Puig A4,5, Bartolomucci A1.

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    PMID: 26946982 PMCID: PMC4841025 DOI: 10.3109/10253890.2016.1151491

  11. Deriving functional beige fat from capillaries.

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    Nat Med. 2016 Mar;22(3):234-6. doi: 10.1038/nm.4056.

    Pellegrinelli V1, Vidal-Puig A1,2.

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    PMID: 26937616 DOI: 10.1038/nm.4056

  12. Mitochondria are required for pro-ageing features of the senescent phenotype.

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    EMBO J. 2016 Apr 1;35(7):724-42. doi: 10.15252/embj.201592862. Epub 2016 Feb 4.

    Correia-Melo C1, Marques FD2, Anderson R2, Hewitt G2, Hewitt R3, Cole J3, Carroll BM2, Miwa S2, Birch J2, Merz A2, Rushton MD2, Charles M2, Jurk D2, Tait SW3, Czapiewski R2, Greaves L4, Nelson G2, Bohlooly-Y M5, Rodriguez-Cuenca S6, Vidal-Puig A6, Mann D7, Saretzki G2, Quarato G8, Green DR8, Adams PD3, von Zglinicki T2, Korolchuk VI2, Passos JF9.

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    PMID: 26848154 PMCID: PMC4818766 DOI: 10.15252/embj.201592862

  13. Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis.

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    Mol Metab. 2015 Nov 11;5(1):19-33. doi: 10.1016/j.molmet.2015.10.005. eCollection 2016.

    Razzoli M1, Frontini A2, Gurney A1, Mondini E2, Cubuk C3, Katz LS4, Cero C1, Bolan PJ5, Dopazo J3, Vidal-Puig A6, Cinti S2, Bartolomucci A1.

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    PMID: 26844204 PMCID: PMC4703853 DOI: 10.1016/j.molmet.2015.10.005

  14. Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance.

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    Sci Rep. 2015 Dec 17;5:18366. doi: 10.1038/srep18366.

    Yew Tan C1, Virtue S1, Murfitt S2, Roberts LD, Phua YH2, Dale M1, Griffin JL2,3, Tinahones F4, Scherer PE5, Vidal-Puig A1,6.

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    PMID: 26679101 PMCID: PMC4683622 DOI: 10.1038/srep18366

  15. Brown Adipose Tissue Thermogenic Capacity Is Regulated by Elovl6.

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    Cell Rep. 2015 Dec 15;13(10):2039-47. doi: 10.1016/j.celrep.2015.11.004. Epub 2015 Nov 25.

    Tan CY1, Virtue S2, Bidault G1, Dale M1, Hagen R1, Griffin JL3, Vidal-Puig A4.

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    PMID: 26628376 PMCID: PMC4688035 DOI: 10.1016/j.celrep.2015.11.004

  16. Unsuppressed lipolysis in adipocytes is linked with enhanced gluconeogenesis and altered bile acid physiology in Insr(P1195L/+) mice fed high-fat-diet.

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    Sci Rep. 2015 Nov 30;5:17565. doi: 10.1038/srep17565.

    Lee EY1, Sakurai K2, Zhang X1, Toda C3, Tanaka T2, Jiang M4, Shirasawa T5, Tachibana K2, Yokote K2, Vidal-Puig A6, Minokoshi Y3, Miki T1.

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    PMID: 26615883 PMCID: PMC4663474 DOI: 10.1038/srep17565

  17. Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans.

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    Nat Commun. 2015 Nov 20;6:8951. doi: 10.1038/ncomms9951.

    Whittle AJ1, Jiang M2,3, Peirce V1, Relat J4, Virtue S1, Ebinuma H5, Fukamachi I5, Yamaguchi T6, Takahashi M7, Murano T2, Tatsuno I6, Takeuchi M8, Nakaseko C8, Jin W9, Jin Z10, Campbell M1, Schneider WJ11, Vidal-Puig A1,12, Bujo H2,3.

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    PMID: 26584636 PMCID: PMC4673879 DOI: 10.1038/ncomms9951

  18. Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity.

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    Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13850-5. doi: 10.1073/pnas.1516004112. Epub 2015 Oct 27.

    Schreiber R1, Hofer P2, Taschler U2, Voshol PJ3, Rechberger GN2, Kotzbeck P2, Jaeger D2, Preiss-Landl K2, Lord CC4, Brown JM4, Haemmerle G2, Zimmermann R2, Vidal-Puig A3, Zechner R1.

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    PMID: 26508640 PMCID: PMC4653216 DOI: 10.1073/pnas.1516004112

  19. Fatty Acid and Glucose Sensors in Hepatic Lipid Metabolism: Implications in NAFLD.

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    Semin Liver Dis. 2015 Aug;35(3):250-61. doi: 10.1055/s-0035-1562945. Epub 2015 Sep 17.

    Vacca M1, Allison M2, Griffin JL1, Vidal-Puig A3.

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    PMID: 26378642 DOI: 10.1055/s-0035-1562945

  20. Regulation of mitochondrial morphology and function by stearoylation of TFR1.

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    Nature. 2015 Sep 3;525(7567):124-8. doi: 10.1038/nature14601. Epub 2015 Jul 27.

    Senyilmaz D1, Virtue S2, Xu X1, Tan CY2, Griffin JL3, Miller AK1, Vidal-Puig A2,4, Teleman AA1.

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    PMID: 26214738 PMCID: PMC4561519 DOI: 10.1038/nature14601

  21. Lipopolysaccharide binding protein is an adipokine involved in the resilience of the mouse adipocyte to inflammation.

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    Diabetologia. 2015 Oct;58(10):2424-34. doi: 10.1007/s00125-015-3692-7. Epub 2015 Jul 23.

    Moreno-Navarrete JM1,2,3, Escoté X4,5,6, Ortega F1,2,3, Camps M7, Ricart W1,2,3, Zorzano A6,7,8, Vendrell J4,5,6, Vidal-Puig A9, Fernández-Real JM10,11,12.

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    PMID: 26201685 DOI: 10.1007/s00125-015-3692-7

  22. Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice.

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    Cell Rep. 2015 Apr 21;11(3):335-43. doi: 10.1016/j.celrep.2015.03.029. Epub 2015 Apr 9.

    Smith MA1, Katsouri L2, Irvine EE2, Hankir MK2, Pedroni SM2, Voshol PJ3, Gordon MW2, Choudhury AI2, Woods A4, Vidal-Puig A3, Carling D4, Withers DJ5.

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    PMID: 25865886 PMCID: PMC4410943 DOI: 10.1016/j.celrep.2015.03.029

  23. Prostaglandin profiling reveals a role for haematopoietic prostaglandin D synthase in adipose tissue macrophage polarisation in mice and humans.

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    Int J Obes (Lond). 2015 Jul;39(7):1151-60. doi: 10.1038/ijo.2015.34. Epub 2015 Mar 24.

    Virtue S1, Masoodi M2, de Weijer BA3, van Eijk M4, Mok CY1, Eiden M5, Dale M1, Pirraco A1, Serlie MJ3, Griffin JL6, Vidal-Puig A1.

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    PMID: 25801691 PMCID: PMC4486370 DOI: 10.1038/ijo.2015.34

  24. Human Adipocytes Induce Inflammation and Atrophy in Muscle Cells During Obesity.

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    Diabetes. 2015 Sep;64(9):3121-34. doi: 10.2337/db14-0796. Epub 2015 Feb 18.

    Pellegrinelli V1, Rouault C2, Rodriguez-Cuenca S3, Albert V2, Edom-Vovard F4, Vidal-Puig A3, Clément K2, Butler-Browne GS4, Lacasa D2.

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    PMID: 25695947 DOI: 10.2337/db14-0796

  25. Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation.

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    Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):506-11. doi: 10.1073/pnas.1414536112. Epub 2014 Dec 24.

    Patel MN1, Bernard WG2, Milev NB1, Cawthorn WP1, Figg N3, Hart D1, Prieur X1, Virtue S1, Hegyi K1, Bonnafous S4, Bailly-Maitre B4, Chu Y5, Griffin JL5, Mallat Z3, Considine RV6, Tran A4, Gual P4, Takeuchi O7, Akira S7, Vidal-Puig A1, Bennett MR3, Sethi JK8.

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    PMID: 25540417 PMCID: PMC4299251 DOI: 10.1073/pnas.1414536112

  26. A Selective Sweep on a Deleterious Mutation in CPT1A in Arctic Populations.

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    Am J Hum Genet. 2014 Oct 23;95(5):584-589. doi: 10.1016/j.ajhg.2014.09.016. [Epub ahead of print]

    Clemente FJ1, Cardona A2, Inchley CE1, Peter BM3, Jacobs G4, Pagani L1, Lawson DJ5, Antão T6, Vicente M1, Mitt M7, DeGiorgio M8, Faltyskova Z1, Xue Y9, Ayub Q9, Szpak M9, Mägi R7, Eriksson A10, Manica A11, Raghavan M12, Rasmussen M12, Rasmussen S13, Willerslev E12, Vidal-Puig A14, Tyler-Smith C9, Villems R15, Nielsen R3, Metspalu M16, Malyarchuk B17, Derenko M17, Kivisild T18.

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    PMID: 25449608 PMCID: PMC4225582 DOI: 10.1016/j.ajhg.2014.09.016

  27. Increased dihydroceramide/ceramide ratio mediated by defective expression of degs1 impairs adipocyte differentiation and function.

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    Diabetes. 2015 Apr;64(4):1180-92. doi: 10.2337/db14-0359. Epub 2014 Oct 28.

    Barbarroja N1, Rodriguez-Cuenca S2, Nygren H3, Camargo A4, Pirraco A5, Relat J6, Cuadrado I7, Pellegrinelli V8, Medina-Gomez G8, Lopez-Pedrera C9, Tinahones FJ10, Symons JD11, Summers SA12, Oresic M13, Vidal-Puig A14.

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    PMID: 25352638 DOI: 10.2337/db14-0359

  28. DLK1/PREF1 regulates nutrient metabolism and protects from steatosis.

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    Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16088-93. doi: 10.1073/pnas.1406119111. Epub 2014 Oct 27.

    Charalambous M1, Da Rocha ST2, Radford EJ2, Medina-Gomez G3, Curran S2, Pinnock SB2, Ferrón SR2, Vidal-Puig A3, Ferguson-Smith AC1.

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    PMID: 25349437 PMCID: PMC4234615 DOI: 10.1073/pnas.1406119111

  29. Understanding disease mechanisms with models of signaling pathway activities.

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    BMC Syst Biol. 2014 Oct 25;8:121. doi: 10.1186/s12918-014-0121-3.

    Sebastian-Leon P1, Vidal E2,3,4, Minguez P5,6, Conesa A7, Tarazona S8, Amadoz A9, Armero C10, Salavert F11,12, Vidal-Puig A13, Montaner D14, Dopazo J15,16,17.

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    PMID: 25344409 PMCID: PMC4213475 DOI: 10.1186/s12918-014-0121-3

  30. Dihydroceramide desaturase 1, the gatekeeper of ceramide induced lipotoxicity.

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    Biochim Biophys Acta. 2015 Jan;1851(1):40-50. doi: 10.1016/j.bbalip.2014.09.021. Epub 2014 Oct 2.

    Rodriguez-Cuenca S1, Barbarroja N2, Vidal-Puig A3.

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    PMID: 25283058 DOI: 10.1016/j.bbalip.2014.09.021

  31. Transducin-like enhancer of split 3 (TLE3) in adipose tissue is increased in situations characterized by decreased PPARγ gene expression.

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    J Mol Med (Berl). 2015 Jan;93(1):83-92. doi: 10.1007/s00109-014-1207-5. Epub 2014 Sep 25.

    Ortega FJ1, Serrano M, Rodriguez-Cuenca S, Moreno-Navarrete JM, Gómez-Serrano M, Sabater M, Rodriguez-Hermosa JI, Xifra G, Ricart W, Peral B, Vidal-Puig A, Fernández-Real JM.

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    PMID: 25249007 DOI: 10.1007/s00109-014-1207-5

  32. Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet.

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    Metabolites. 2012 Jun 18;2(2):366-81. doi: 10.3390/metabo2020366.

    McCombie G1, Medina-Gomez G2, Lelliott CJ3, Vidal-Puig A2, Griffin JL4.

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    PMID: 24957515 PMCID: PMC3901207 DOI: 10.3390/metabo2020366

  33. The different shades of fat.

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    Nature. 2014 Jun 5;510(7503):76-83. doi: 10.1038/nature13477.

    Peirce V1, Carobbio S2, Vidal-Puig A2.

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    PMID: 24899307 DOI: 10.1038/nature13477

  34. Brown adipose tissue in the treatment of obesity and diabetes: Are we hot enough?

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    J Diabetes Investig. 2011 Oct 7;2(5):341-50. doi: 10.1111/j.2040-1124.2011.00158.x.

    Tan CY1, Ishikawa K1, Virtue S1, Vidal-Puig A1.

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    PMID: 24843510 PMCID: PMC4019299 DOI: 10.1111/j.2040-1124.2011.00158.x

  35. Response to letter regarding article, “Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans”.

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    Circulation. 2014 Mar 25;129(12):e408. doi: 10.1161/CIRCULATIONAHA.113.008032.

    Yu E1, Calvert PA, Mercer JR, Harrison J, Baker L, Figg NL, Kumar S, Wang JJ, Hurst LA, Obaid DR, Logan A, West NE, Clarke MC, Vidal-Puig A, Murphy MP, Bennett MR.

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    PMID: 24664223 DOI: 10.1161/CIRCULATIONAHA.113.008032

  36. Regulation of glucose homoeostasis by brown adipose tissue.

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    Lancet Diabetes Endocrinol. 2013 Dec;1(4):353-60. doi: 10.1016/S2213-8587(13)70055-X. Epub 2013 Aug 27.

    Peirce V1, Vidal-Puig A2.

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    PMID: 24622420 DOI: 10.1016/S2213-8587(13)70055-X

  37. Methods for performing lipidomics in white adipose tissue.

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    Methods Enzymol. 2014;538:211-31. doi: 10.1016/B978-0-12-800280-3.00012-8.

    Roberts LD1, West JA1, Vidal-Puig A2, Griffin JL3.

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    PMID: 24529441 DOI: 10.1016/B978-0-12-800280-3.00012-8

  38. Adipose tissue expandability, lipotoxicity and the metabolic syndrome.

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    Endocrinol Nutr. 2013;60 Suppl 1:39-43.

    Vidal-Puig A.

    PMID: 24490226

  39. Central obesity and altered peripheral adipose tissue gene expression characterize the NAFLD patient with insulin resistance: Role of nutrition and insulin challenge.

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    Nutrition. 2014 Feb;30(2):177-85. doi: 10.1016/j.nut.2013.07.017.

    Paniagua JA1, Escandell-Morales JM2, Gil-Contreras D2, Berral de la Rosa FJ3, Romero-Jimenez M2, Gómez-Urbano A2, Sanchez-Lopez A2, Bellido E4, Poyato A5, Calatayud B2, Vidal-Puig AJ6.

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    PMID: 24377452 DOI: 10.1016/j.nut.2013.07.017

  40. Psychosocial stress induces hyperphagia and exacerbates diet-induced insulin resistance and the manifestations of the Metabolic Syndrome.

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    Psychoneuroendocrinology. 2013 Dec;38(12):2933-42. doi: 10.1016/j.psyneuen.2013.07.022. Epub 2013 Sep 2.

    Sanghez V1, Razzoli M, Carobbio S, Campbell M, McCallum J, Cero C, Ceresini G, Cabassi A, Govoni P, Franceschini P, de Santis V, Gurney A, Ninkovic I, Parmigiani S, Palanza P, Vidal-Puig A, Bartolomucci A.

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    PMID: 24060458 DOI: 10.1016/j.psyneuen.2013.07.022

  41. Adipogenesis: new insights into brown adipose tissue differentiation.

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    J Mol Endocrinol. 2013 Nov 26;51(3):T75-85. doi: 10.1530/JME-13-0158. Print 2013 Dec.

    Carobbio S1, Rosen B, Vidal-Puig A.

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    PMID: 24041933 DOI: 10.1530/JME-13-0158

  42. A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction.

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    Diabetologia. 2013 Nov;56(11):2524-37. doi: 10.1007/s00125-013-3015-9. Epub 2013 Aug 21.

    Moreno-Navarrete JM1, Escoté X, Ortega F, Serino M, Campbell M, Michalski MC, Laville M, Xifra G, Luche E, Domingo P, Sabater M, Pardo G, Waget A, Salvador J, Giralt M, Rodriguez-Hermosa JI, Camps M, Kolditz CI, Viguerie N, Galitzky J, Decaunes P, Ricart W, Frühbeck G, Villarroya F, Mingrone G, Langin D, Zorzano A, Vidal H, Vendrell J, Burcelin R, Vidal-Puig A, Fernández-Real JM.

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    PMID: 23963324 DOI: 10.1007/s00125-013-3015-9

  43. Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity.

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    Diabetes. 2013 Nov;62(11):3697-708. doi: 10.2337/db12-1748. Epub 2013 Aug 6.

    Carobbio S1, Hagen RM, Lelliott CJ, Slawik M, Medina-Gomez G, Tan CY, Sicard A, Atherton HJ, Barbarroja N, Bjursell M, Bohlooly-Y M, Virtue S, Tuthill A, Lefai E, Laville M, Wu T, Considine RV, Vidal H, Langin D, Oresic M, Tinahones FJ, Fernandez-Real JM, Griffin JL, Sethi JK, López M, Vidal-Puig A.

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    PMID: 23919961 PMCID: PMC3806615 DOI: 10.2337/db12-1748

  44. Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans.

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    Circulation. 2013 Aug 13;128(7):702-12. doi: 10.1161/CIRCULATIONAHA.113.002271. Epub 2013 Jul 10.

    Yu E1, Calvert PA, Mercer JR, Harrison J, Baker L, Figg NL, Kumar S, Wang JC, Hurst LA, Obaid DR, Logan A, West NE, Clarke MC, Vidal-Puig A, Murphy MP, Bennett MR.

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  52. Identification of novel type 2 diabetes candidate genes involved in the crosstalk between the mitochondrial and the insulin signaling systems.

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  63. Ablation of Pparg2 impairs lipolysis and reveals murine strain differences in lipolytic responses.

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  69. Postprandial inflammatory response in adipose tissue of patients with metabolic syndrome after the intake of different dietary models.

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  72. Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats.

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  73. Origins of metabolic complications in obesity: ectopic fat accumulation. The importance of the qualitative aspect of lipotoxicity.

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  79. Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation.

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  81. Deletion of the metabolic transcriptional coactivator PGC1β induces cardiac arrhythmia.

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  83. Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) is a metabolic regulator of intestinal epithelial cell fate.

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  85. Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice.

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  88. Electrical and optical spectroscopy for quantitative screening of hepatic steatosis in donor livers.

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    Mercer JR, Cheng KK, Figg N, Gorenne I, Mahmoudi M, Griffin J, Vidal-Puig A, Logan A, Murphy MP, Bennett M.

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  92. The obese healthy paradox: is inflammation the answer?

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    Biochem J. 2010 Aug 15;430(1):141-9. doi: 10.1042/BJ20100285.

    Barbarroja N, López-Pedrera R, Mayas MD, García-Fuentes E, Garrido-Sánchez L, Macías-González M, El Bekay R, Vidal-Puig A, Tinahones FJ.

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  93. Secreted frizzled-related protein 1 regulates adipose tissue expansion and is dysregulated in severe obesity.

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    Int J Obes (Lond). 2010 Dec;34(12):1695-705. doi: 10.1038/ijo.2010.107. Epub 2010 Jun 1.

    Lagathu C, Christodoulides C, Tan CY, Virtue S, Laudes M, Campbell M, Ishikawa K, Ortega F, Tinahones FJ, Fernández-Real JM, Orešič M, Sethi JK, Vidal-Puig A.

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  94. No association between polymorphisms in the INSIG1 gene and the risk of type 2 diabetes and related traits.

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    Szopa M, Meirhaeghe A, Luan J, Moreno LA, Gonzalez-Gross M, Vidal-Puig A, Cooper C, Hagen R, Amouyel P, Wareham NJ, Loos RJ.

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  95. An allostatic control of membrane lipid composition by SREBP1.

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    FEBS Lett. 2010 Jun 18;584(12):2689-98. doi: 10.1016/j.febslet.2010.04.004. Epub 2010 Apr 10.

    Hagen RM, Rodriguez-Cuenca S, Vidal-Puig A.

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  96. Ghrelin effects on neuropeptides in the rat hypothalamus depend on fatty acid metabolism actions on BSX but not on gender.

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    FASEB J. 2010 Aug;24(8):2670-9. doi: 10.1096/fj.09-150672. Epub 2010 Mar 24.

    Lage R, Vázquez MJ, Varela L, Saha AK, Vidal-Puig A, Nogueiras R, Diéguez C, López M.

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    PMID: 20335227 [PubMed – indexed for MEDLINE] PMCID: PMC3230529

  97. Extracellular fatty acid synthase: a possible surrogate biomarker of insulin resistance.

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    Diabetes. 2010 Jun;59(6):1506-11. doi: 10.2337/db09-1756. Epub 2010 Mar 18.

    Fernandez-Real JM, Menendez JA, Moreno-Navarrete JM, Blüher M, Vazquez-Martin A, Vázquez MJ, Ortega F, Diéguez C, Frühbeck G, Ricart W, Vidal-Puig A.

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  98. Wnt signalling and the control of cellular metabolism.

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    Biochem J. 2010 Mar 15;427(1):1-17. doi: 10.1042/BJ20091866.

    Sethi JK, Vidal-Puig A.

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    PMID: 20226003 [PubMed – indexed for MEDLINE]

  99. Abdominal subcutaneous adipose tissue morphology in a patient with a dominant-negative mutation (P467L) in the nuclear receptor peroxisome proliferator-activated receptor-gamma (PPARG) gene.

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    Nutr Metab Cardiovasc Dis. 2010 Mar;20(3):e11-2. doi: 10.1016/j.numecd.2009.10.018. Epub 2010 Feb 12.

    Boiani R, Cinti S, Savage DB, Vidal-Puig A, O’Rahilly S.

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    PMID: 20153617 [PubMed – indexed for MEDLINE]

  100. Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome–an allostatic perspective.

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    Biochim Biophys Acta. 2010 Mar;1801(3):338-49. doi: 10.1016/j.bbalip.2009.12.006. Epub 2010 Jan 6.

    Virtue S, Vidal-Puig A.

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    PMID: 20056169 [PubMed – indexed for MEDLINE]

  101. Obesity as a clinical and public health problem: is there a need for a new definition based on lipotoxicity effects?

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    Biochim Biophys Acta. 2010 Mar;1801(3):400-4. doi: 10.1016/j.bbalip.2009.12.011. Epub 2010 Jan 4.

    Sørensen TI, Virtue S, Vidal-Puig A.

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  102. Special issue on lipotoxicity.

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    Biochim Biophys Acta. 2010 Mar;1801(3):207-8. doi: 10.1016/j.bbalip.2009.12.010. Epub 2010 Jan 4.

    Vidal-Puig A, Unger RH.

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    PMID: 20045080 [PubMed – indexed for MEDLINE]

  103. [Adipose tissue as a therapeutic target in obesity].

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    Endocrinol Nutr. 2009 Oct;56(8):404-11. doi: 10.1016/S1575-0922(09)72710-X.

    Medina-Gómez G, Vidal-Puig A.

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  104. Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.

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    Free Radic Biol Med. 2010 Jan 1;48(1):161-72. doi: 10.1016/j.freeradbiomed.2009.10.039. Epub 2009 Oct 23.

    Rodriguez-Cuenca S, Cochemé HM, Logan A, Abakumova I, Prime TA, Rose C, Vidal-Puig A, Smith AC, Rubinsztein DC, Fearnley IM, Jones BA, Pope S, Heales SJ, Lam BY, Neogi SG, McFarlane I, James AM, Smith RA, Murphy MP.

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  105. Adaptation and failure of pancreatic beta cells in murine models with different degrees of metabolic syndrome.

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    Dis Model Mech. 2009 Nov-Dec;2(11-12):582-92. doi: 10.1242/dmm.003251. Epub 2009 Oct 19.

    Medina-Gomez G, Yetukuri L, Velagapudi V, Campbell M, Blount M, Jimenez-Linan M, Ros M, Oresic M, Vidal-Puig A.

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    PMID: 19841237 [PubMed – indexed for MEDLINE] PMCID: PMC2773727

  106. PPARs and adipocyte function.

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    Mol Cell Endocrinol. 2010 Apr 29;318(1-2):61-8. doi: 10.1016/j.mce.2009.09.014. Epub 2009 Sep 20.

    Christodoulides C, Vidal-Puig A.

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    PMID: 19772894 [PubMed – indexed for MEDLINE]

  107. Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria.

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    J Bioenerg Biomembr. 2009 Aug;41(4):335-42. doi: 10.1007/s10863-009-9232-8. Epub 2009 Aug 25.

    Parker N, Crichton PG, Vidal-Puig AJ, Brand MD.

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    PMID: 19705265 [PubMed – indexed for MEDLINE]

  108. Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels.

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    Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13100-5. doi: 10.1073/pnas.0903723106. Epub 2009 Jul 21.

    Singh A, Wirtz M, Parker N, Hogan M, Strahler J, Michailidis G, Schmidt S, Vidal-Puig A, Diano S, Andrews P, Brand MD, Friedman J.

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    PMID: 19622746 [PubMed – indexed for MEDLINE] PMCID: PMC2713753

  109. Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1.

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    Biosci Rep. 2009 Dec 15;30(3):187-92. doi: 10.1042/BSR20090063.

    Crichton PG, Parker N, Vidal-Puig AJ, Brand MD.

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    PMID: 19622065 [PubMed – indexed for MEDLINE] PMCID: PMC2805926

  110. Metabolic phenotyping of a model of adipocyte differentiation.

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    Physiol Genomics. 2009 Oct 7;39(2):109-19. doi: 10.1152/physiolgenomics.90365.2008. Epub 2009 Jul 14.

    Roberts LD, Virtue S, Vidal-Puig A, Nicholls AW, Griffin JL.

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    PMID: 19602617 [PubMed – indexed for MEDLINE] PMCID: PMC2765066

  111. Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.

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    Biochim Biophys Acta. 2009 Dec;1787(12):1451-7. doi: 10.1016/j.bbabio.2009.06.005. Epub 2009 Jun 17.

    Parker N, Vidal-Puig AJ, Azzu V, Brand MD.

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    PMID: 19539600 [PubMed – indexed for MEDLINE] PMCID: PMC2741566

  112. PGC-1beta: a co-activator that sets the tone for both basal and stress-stimulated mitochondrial activity.

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    Adv Exp Med Biol. 2009;646:133-9. doi: 10.1007/978-1-4020-9173-5_15.

    Lelliott CJ, Vidal-Puig A.

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    PMID: 19536672 [PubMed – indexed for MEDLINE]

  113. Defective peroxisomal proliferators activated receptor gamma activity due to dominant-negative mutation synergizes with hypertension to accelerate cardiac fibrosis in mice.

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    Eur J Heart Fail. 2009 Jun;11(6):533-41. doi: 10.1093/eurjhf/hfp048. Epub 2009 Apr 24.

    Kis A, Murdoch C, Zhang M, Siva A, Rodriguez-Cuenca S, Carobbio S, Lukasik A, Blount M, O’Rahilly S, Gray SL, Shah AM, Vidal-Puig A.

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    PMID: 19395708 [PubMed – indexed for MEDLINE] PMCID: PMC2686026

  114. CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance.

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    Cell Metab. 2009 Apr;9(4):339-49. doi: 10.1016/j.cmet.2009.03.002.

    Chavey C, Lazennec G, Lagarrigue S, Clapé C, Iankova I, Teyssier J, Annicotte JS, Schmidt J, Mataki C, Yamamoto H, Sanches R, Guma A, Stich V, Vitkova M, Jardin-Watelet B, Renard E, Strieter R, Tuthill A, Hotamisligil GS, Vidal-Puig A, Zorzano A, Langin D, Fajas L.

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    PMID: 19356715 [PubMed – indexed for MEDLINE] PMCID: PMC2804846

  115. Integrating post-genomic approaches as a strategy to advance our understanding of health and disease.

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    Genome Med. 2009 Mar 30;1(3):35. doi: 10.1186/gm35.

    Tang J, Tan CY, Oresic M, Vidal-Puig A.

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    PMID: 19341506 [PubMed] PMCID: PMC2664946

  116. Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation.

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    Nat Med. 2009 Mar;15(3):259-66. doi: 10.1038/nm.1910. Epub 2009 Mar 1.

    Ishii KA, Fumoto T, Iwai K, Takeshita S, Ito M, Shimohata N, Aburatani H, Taketani S, Lelliott CJ, Vidal-Puig A, Ikeda K.

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  117. Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network.

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    Diabetes. 2009 Mar;58(3):609-19. doi: 10.2337/db08-1180. Epub 2008 Dec 10.

    Lagathu C, Christodoulides C, Virtue S, Cawthorn WP, Franzin C, Kimber WA, Nora ED, Campbell M, Medina-Gomez G, Cheyette BN, Vidal-Puig AJ, Sethi JK.

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    PMID: 19073771 [PubMed – indexed for MEDLINE] PMCID: PMC2646059

  118. Adipogenesis and WNT signalling.

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    Trends Endocrinol Metab. 2009 Jan;20(1):16-24. doi: 10.1016/j.tem.2008.09.002. Epub 2008 Nov 13.

    Christodoulides C, Lagathu C, Sethi JK, Vidal-Puig A.

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    PMID: 19008118 [PubMed – indexed for MEDLINE]

  119. Wnt signalling at the crossroads of nutritional regulation.

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    Biochem J. 2008 Dec 1;416(2):e11-3. doi: 10.1042/BJ20082074.

    Sethi JK, Vidal-Puig AJ.

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    PMID: 18990086 [PubMed – indexed for MEDLINE]

  120. UCPs–unlikely calcium porters.

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    Nat Cell Biol. 2008 Nov;10(11):1235-7; author reply 1237-40. doi: 10.1038/ncb1108-1235.

    Brookes PS, Parker N, Buckingham JA, Vidal-Puig A, Halestrap AP, Gunter TE, Nicholls DG, Bernardi P, Lemasters JJ, Brand MD.

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    PMID: 18978830 [PubMed – indexed for MEDLINE] PMCID: PMC2691551

  121. AMPK: a metabolic gauge regulating whole-body energy homeostasis.

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    Trends Mol Med. 2008 Dec;14(12):539-49. doi: 10.1016/j.molmed.2008.09.007. Epub 2008 Nov 1.

    Lage R, Diéguez C, Vidal-Puig A, López M.

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    PMID: 18977694 [PubMed – indexed for MEDLINE]

  122. Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta.

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    PLoS One. 2008;3(10):e3613. doi: 10.1371/journal.pone.0003613. Epub 2008 Oct 31.

    Liesa M, Borda-d’Agua B, Medina-Gómez G, Lelliott CJ, Paz JC, Rojo M, Palacín M, Vidal-Puig A, Zorzano A.

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    PMID: 18974884 [PubMed – indexed for MEDLINE] PMCID: PMC2570954

  123. Lipidomics: a new window to biomedical frontiers.

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    Trends Biotechnol. 2008 Dec;26(12):647-52. doi: 10.1016/j.tibtech.2008.09.001. Epub 2008 Oct 23.

    Oresic M, Hänninen VA, Vidal-Puig A.

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    PMID: 18951641 [PubMed – indexed for MEDLINE]

  124. Adipose tissue expandability and the metabolic syndrome.

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    Genes Nutr. 2007 Oct;2(1):41-5. doi: 10.1007/s12263-007-0014-9.

    Slawik M, Vidal-Puig AJ.

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  125. It’s not how fat you are, it’s what you do with it that counts.

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    PLoS Biol. 2008 Sep 23;6(9):e237. doi: 10.1371/journal.pbio.0060237.

    Virtue S, Vidal-Puig A.

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    PMID: 18816166 [PubMed – indexed for MEDLINE] PMCID: PMC2553843

  126. Adipose tissue expandability: the metabolic problems of obesity may arise from the inability to become more obese.

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    Biochem Soc Trans. 2008 Oct;36(Pt 5):935-40. doi: 10.1042/BST0360935.

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  127. Brain lipogenesis and regulation of energy metabolism.

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    Curr Opin Clin Nutr Metab Care. 2008 Jul;11(4):483-90. doi: 10.1097/MCO.0b013e328302f3d8.

    López M, Vidal-Puig A.

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    PMID: 18542011 [PubMed – indexed for MEDLINE]

  128. Central resistin regulates hypothalamic and peripheral lipid metabolism in a nutritional-dependent fashion.

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    Endocrinology. 2008 Sep;149(9):4534-43. doi: 10.1210/en.2007-1708. Epub 2008 May 22.

    Vázquez MJ, González CR, Varela L, Lage R, Tovar S, Sangiao-Alvarellos S, Williams LM, Vidal-Puig A, Nogueiras R, López M, Diéguez C.

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  129. Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

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    Cell Metab. 2008 May;7(5):389-99. doi: 10.1016/j.cmet.2008.03.006.

    López M, Lage R, Saha AK, Pérez-Tilve D, Vázquez MJ, Varela L, Sangiao-Alvarellos S, Tovar S, Raghay K, Rodríguez-Cuenca S, Deoliveira RM, Castañeda T, Datta R, Dong JZ, Culler M, Sleeman MW, Alvarez CV, Gallego R, Lelliott CJ, Carling D, Tschöp MH, Diéguez C, Vidal-Puig A.

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  130. Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition.

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    J Clin Endocrinol Metab. 2008 Jul;93(7):2859-65. doi: 10.1210/jc.2007-2759. Epub 2008 Apr 29.

    Barber TM, Hazell M, Christodoulides C, Golding SJ, Alvey C, Burling K, Vidal-Puig A, Groome NP, Wass JA, Franks S, McCarthy MI.

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  131. Current challenges in metabolomics for diabetes research: a vital functional genomic tool or just a ploy for gaining funding?

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    Physiol Genomics. 2008 Jun 12;34(1):1-5. doi: 10.1152/physiolgenomics.00009.2008. Epub 2008 Apr 15.

    Griffin JL, Vidal-Puig A.

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  132. Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential.

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    Biosci Rep. 2008 Apr;28(2):83-8. doi: 10.1042/BSR20080002.

    Parker N, Vidal-Puig A, Brand MD.

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    PMID: 18384278 [PubMed – indexed for MEDLINE] PMCID: PMC2518262

  133. Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability.

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    Endocrinology. 2008 Jun;149(6):3009-15. doi: 10.1210/en.2007-1684. Epub 2008 Feb 28.

    Nogueiras R, López M, Lage R, Perez-Tilve D, Pfluger P, Mendieta-Zerón H, Sakkou M, Wiedmer P, Benoit SC, Datta R, Dong JZ, Culler M, Sleeman M, Vidal-Puig A, Horvath T, Treier M, Diéguez C, Tschöp MH.

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  134. The metabolic profile of early Huntington’s disease–a combined human and transgenic mouse study.

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    Exp Neurol. 2008 Apr;210(2):691-8. doi: 10.1016/j.expneurol.2007.12.026. Epub 2008 Jan 19.

    Goodman AO, Murgatroyd PR, Medina-Gomez G, Wood NI, Finer N, Vidal-Puig AJ, Morton AJ, Barker RA.

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  135. Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria.

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    Biochem J. 2008 May 15;412(1):131-9. doi: 10.1042/BJ20080006.

    Parker N, Affourtit C, Vidal-Puig A, Brand MD.

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    PMID: 18251717 [PubMed – indexed for MEDLINE] PMCID: PMC2474556

  136. A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.

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    PLoS Med. 2008 Jan 29;5(1):e27. doi: 10.1371/journal.pmed.0050027.

    Savage DB, Zhai L, Ravikumar B, Choi CS, Snaar JE, McGuire AC, Wou SE, Medina-Gomez G, Kim S, Bock CB, Segvich DM, Solanky B, Deelchand D, Vidal-Puig A, Wareham NJ, Shulman GI, Karpe F, Taylor R, Pederson BA, Roach PJ, O’Rahilly S, DePaoli-Roach AA.

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  137. Informatics and computational strategies for the study of lipids.

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    Mol Biosyst. 2008 Feb;4(2):121-7. doi: 10.1039/b715468b. Epub 2007 Dec 18.

    Yetukuri L, Ekroos K, Vidal-Puig A, Oresic M.

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  138. Feeding and metabolism in mice lacking pituitary adenylate cyclase-activating polypeptide.

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    Endocrinology. 2008 Apr;149(4):1571-80. Epub 2007 Dec 27.

    Adams BA, Gray SL, Isaac ER, Bianco AC, Vidal-Puig AJ, Sherwood NM.

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  139. Critical assessment of the current guidelines for the management and treatment of morbidly obese patients.

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    J Endocrinol Invest. 2007 Nov;30(10):844-52.

    Burguera B, Agusti A, Arner P, Baltasar A, Barbe F, Barcelo A, Breton I, Cabanes T, Casanueva FF, Couce ME, Dieguez C, Fiol M, Fernandez Real JM, Formiguera X, Fruhbeck G, Garcia Romero M, Garcia Sanz M, Ghigo E, Gomis R, Higa K, Ibarra O, Lacy A, Larrad A, Masmiquel L, Moizé V, Moreno B, Moreiro J, Ricart W, Riesco M, Salinas R, Salvador J, Pi-Sunyer FX, Scopinaro N, Sjostrom L, Pagan A, Pereg V, Sánchez Pernaute A, Torres A, Urgeles JR, Vidal-Puig A, Vidal J, Vila M.

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  140. Adipogenesis and lipotoxicity: role of peroxisome proliferator-activated receptor gamma (PPARgamma) and PPARgammacoactivator-1 (PGC1).

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    Public Health Nutr. 2007 Oct;10(10A):1132-7.

    Medina-Gomez G, Gray S, Vidal-Puig A.

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  141. Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules.

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    Diabetologia. 2008 Jan;51(1):147-54. Epub 2007 Nov 10.

    Schinner S, Ulgen F, Papewalis C, Schott M, Woelk A, Vidal-Puig A, Scherbaum WA.

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  142. A MUFA-rich diet improves posprandial glucose, lipid and GLP-1 responses in insulin-resistant subjects.

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    J Am Coll Nutr. 2007 Oct;26(5):434-44.

    Paniagua JA, de la Sacristana AG, Sánchez E, Romero I, Vidal-Puig A, Berral FJ, Escribano A, Moyano MJ, Peréz-Martinez P, López-Miranda J, Pérez-Jiménez F.

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  143. Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.

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    J Clin Invest. 2007 Sep;117(9):2539-52.

    Chakravarthy MV, Zhu Y, López M, Yin L, Wozniak DF, Coleman T, Hu Z, Wolfgang M, Vidal-Puig A, Lane MD, Semenkovich CF.

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  144. Orexin expression is regulated by alpha-melanocyte-stimulating hormone.

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    J Neuroendocrinol. 2007 Sep;19(9):703-7.

    López M, Lage R, Tung YC, Challis BG, Varela L, Virtue S, O’Rahilly S, Vidal-Puig A, Diéguez C, Coll AP.

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  145. Adipose tissue expandability in the maintenance of metabolic homeostasis.

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    Nutr Rev. 2007 Jun;65(6 Pt 2):S7-12.

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  146. Targeting fat to prevent diabetes.

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    Cell Metab. 2007 May;5(5):323-5.

    Sethi JK, Vidal-Puig AJ.

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    PMID: 17488634 [PubMed – indexed for MEDLINE]

  147. PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.

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    PLoS Genet. 2007 Apr 27;3(4):e64.

    Medina-Gomez G, Gray SL, Yetukuri L, Shimomura K, Virtue S, Campbell M, Curtis RK, Jimenez-Linan M, Blount M, Yeo GS, Lopez M, Seppänen-Laakso T, Ashcroft FM, Oresic M, Vidal-Puig A.

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    PMID: 17465682 [PubMed – indexed for MEDLINE] PMCID: PMC1857730

  148. Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis.

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    BMC Syst Biol. 2007 Feb 15;1:12.

    Yetukuri L, Katajamaa M, Medina-Gomez G, Seppänen-Laakso T, Vidal-Puig A, Oresic M.

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    PMID: 17408502 [PubMed – indexed for MEDLINE] PMCID: PMC1839890

  149. Monounsaturated fat-rich diet prevents central body fat distribution and decreases postprandial adiponectin expression induced by a carbohydrate-rich diet in insulin-resistant subjects.

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    Diabetes Care. 2007 Jul;30(7):1717-23. Epub 2007 Mar 23.

    Paniagua JA, Gallego de la Sacristana A, Romero I, Vidal-Puig A, Latre JM, Sanchez E, Perez-Martinez P, Lopez-Miranda J, Perez-Jimenez F.

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    PMID: 17384344 [PubMed – indexed for MEDLINE]

  150. Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation.

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    J Lipid Res. 2007 Jun;48(6):1253-62. Epub 2007 Mar 20.

    Sethi JK, Vidal-Puig AJ.

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    PMID: 17374880 [PubMed – indexed for MEDLINE]

  151. Hypothalamic fatty acid metabolism: a housekeeping pathway that regulates food intake.

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    Bioessays. 2007 Mar;29(3):248-61.

    López M, Lelliott CJ, Vidal-Puig A.

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    PMID: 17295284 [PubMed – indexed for MEDLINE]

  152. IGF-binding protein-2 protects against the development of obesity and insulin resistance.

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    Diabetes. 2007 Feb;56(2):285-94.

    Wheatcroft SB, Kearney MT, Shah AM, Ezzat VA, Miell JR, Modo M, Williams SC, Cawthorn WP, Medina-Gomez G, Vidal-Puig A, Sethi JK, Crossey PA.

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    PMID: 17259371 [PubMed – indexed for MEDLINE]

  153. Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.

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    PLoS Biol. 2006 Nov;4(11):e369.

    Lelliott CJ, Medina-Gomez G, Petrovic N, Kis A, Feldmann HM, Bjursell M, Parker N, Curtis K, Campbell M, Hu P, Zhang D, Litwin SE, Zaha VG, Fountain KT, Boudina S, Jimenez-Linan M, Blount M, Lopez M, Meirhaeghe A, Bohlooly-Y M, Storlien L, Strömstedt M, Snaith M, Oresic M, Abel ED, Cannon B, Vidal-Puig A.

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    PMID: 17090215 [PubMed – indexed for MEDLINE] PMCID: PMC1634886

  154. Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor gamma function (P465L PPARgamma) in mice.

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    Diabetes. 2006 Oct;55(10):2669-77.

    Gray SL, Nora ED, Grosse J, Manieri M, Stoeger T, Medina-Gomez G, Burling K, Wattler S, Russ A, Yeo GS, Chatterjee VK, O’Rahilly S, Voshol PJ, Cinti S, Vidal-Puig A.

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    PMID: 17003330 [PubMed – indexed for MEDLINE]

  155. Decreased brown adipocyte recruitment and thermogenic capacity in mice with impaired peroxisome proliferator-activated receptor (P465L PPARgamma) function.

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    Endocrinology. 2006 Dec;147(12):5708-14. Epub 2006 Sep 15.

    Gray SL, Dalla Nora E, Backlund EC, Manieri M, Virtue S, Noland RC, O’Rahilly S, Cortright RN, Cinti S, Cannon B, Vidal-Puig A.

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    PMID: 16980437 [PubMed – indexed for MEDLINE]

  156. Metabolomic approaches to phenotype characterization and applications to complex diseases.

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    Expert Rev Mol Diagn. 2006 Jul;6(4):575-85.

    Oresic M, Vidal-Puig A, Hänninen V.

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    PMID: 16824031 [PubMed – indexed for MEDLINE]

  157. The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis.

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    J Cell Sci. 2006 Jun 15;119(Pt 12):2613-20.

    Christodoulides C, Laudes M, Cawthorn WP, Schinner S, Soos M, O’Rahilly S, Sethi JK, Vidal-Puig A.

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    PMID: 16763196 [PubMed – indexed for MEDLINE]

  158. [Obesity, MODY and juvenile diabetes: a new diagnostic challenge].

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    Med Clin (Barc). 2006 May 6;126(17):656-7.

    Vidal-Puig A.

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    PMID: 16759566 [PubMed – indexed for MEDLINE]

  159. Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA.

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    Diabetes. 2006 May;55(5):1327-36.

    López M, Lelliott CJ, Tovar S, Kimber W, Gallego R, Virtue S, Blount M, Vázquez MJ, Finer N, Powles TJ, O’Rahilly S, Saha AK, Diéguez C, Vidal-Puig AJ.

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    PMID: 16644689 [PubMed – indexed for MEDLINE]

  160. Lipotoxicity, overnutrition and energy metabolism in aging.

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    Ageing Res Rev. 2006 May;5(2):144-64. Epub 2006 Apr 21.

    Slawik M, Vidal-Puig AJ.

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    PMID: 16630750 [PubMed – indexed for MEDLINE]

  161. An update on visfatin/pre-B cell colony-enhancing factor, an ubiquitously expressed, illusive cytokine that is regulated in obesity.

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    Curr Opin Lipidol. 2006 Apr;17(2):128-31.

    Stephens JM, Vidal-Puig AJ.

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    PMID: 16531748 [PubMed – indexed for MEDLINE]

  162. Anaplerotic roles of pyruvate carboxylase in mammalian tissues.

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    Cell Mol Life Sci. 2006 Apr;63(7-8):843-54.

    Jitrapakdee S, Vidal-Puig A, Wallace JC.

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    PMID: 16505973 [PubMed – indexed for MEDLINE]

  163. WNT10B mutations in human obesity.

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    Diabetologia. 2006 Apr;49(4):678-84. Epub 2006 Feb 14.

    Christodoulides C, Scarda A, Granzotto M, Milan G, Dalla Nora E, Keogh J, De Pergola G, Stirling H, Pannacciulli N, Sethi JK, Federspil G, Vidal-Puig A, Farooqi IS, O’Rahilly S, Vettor R.

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    PMID: 16477437 [PubMed – indexed for MEDLINE]

  164. Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice.

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    Diabetologia. 2006 Mar;49(3):552-61. Epub 2006 Jan 11.

    Simmgen M, Knauf C, Lopez M, Choudhury AI, Charalambous M, Cantley J, Bedford DC, Claret M, Iglesias MA, Heffron H, Cani PD, Vidal-Puig A, Burcelin R, Withers DJ.

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    PMID: 16404553 [PubMed – indexed for MEDLINE]

  165. Mouse models of PPAR-gamma deficiency: dissecting PPAR-gamma’s role in metabolic homoeostasis.

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    Biochem Soc Trans. 2005 Nov;33(Pt 5):1053-8.

    Gray SL, Dalla Nora E, Vidal-Puig AJ.

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    PMID: 16246044 [PubMed – indexed for MEDLINE]

  166. Visfatin: the missing link between intra-abdominal obesity and diabetes?

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    Trends Mol Med. 2005 Aug;11(8):344-7.

    Sethi JK, Vidal-Puig A.

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    PMID: 16005682 [PubMed – indexed for MEDLINE]

  167. Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis.

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    FASEB J. 2005 Jul;19(9):1108-19.

    Lelliott CJ, López M, Curtis RK, Parker N, Laudes M, Yeo G, Jimenez-Liñan M, Grosse J, Saha AK, Wiggins D, Hauton D, Brand MD, O’Rahilly S, Griffin JL, Gibbons GF, Vidal-Puig A.

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    PMID: 15985534 [PubMed – indexed for MEDLINE]

  168. Pathways to the analysis of microarray data.

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    Trends Biotechnol. 2005 Aug;23(8):429-35.

    Curtis RK, Oresic M, Vidal-Puig A.

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    PMID: 15950303 [PubMed – indexed for MEDLINE]

  169. Gateway to the metabolic syndrome.

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    Nat Med. 2005 Jun;11(6):602-3.

    Medina-Gomez G, Vidal-Puig A.

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    PMID: 15937471 [PubMed – indexed for MEDLINE]

  170. The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform.

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    Diabetes. 2005 Jun;54(6):1706-16.

    Medina-Gomez G, Virtue S, Lelliott C, Boiani R, Campbell M, Christodoulides C, Perrin C, Jimenez-Linan M, Blount M, Dixon J, Zahn D, Thresher RR, Aparicio S, Carlton M, Colledge WH, Kettunen MI, Seppänen-Laakso T, Sethi JK, O’Rahilly S, Brindle K, Cinti S, Oresic M, Burcelin R, Vidal-Puig A.

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    PMID: 15919792 [PubMed – indexed for MEDLINE]

  171. The peroxisome proliferator-activated receptor-gamma regulates murine pyruvate carboxylase gene expression in vivo and in vitro.

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    J Biol Chem. 2005 Jul 22;280(29):27466-76. Epub 2005 May 25.

    Jitrapakdee S, Slawik M, Medina-Gomez G, Campbell M, Wallace JC, Sethi JK, O’rahilly S, Vidal-Puig AJ.

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    PMID: 15917242 [PubMed – indexed for MEDLINE]

  172. Regulation of adiponectin expression in human adipocytes: effects of adiposity, glucocorticoids, and tumor necrosis factor alpha.

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    Obes Res. 2005 Apr;13(4):662-9.

    Degawa-Yamauchi M, Moss KA, Bovenkerk JE, Shankar SS, Morrison CL, Lelliott CJ, Vidal-Puig A, Jones R, Considine RV.

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    PMID: 15897474 [PubMed – indexed for MEDLINE]

  173. A dominant negative human peroxisome proliferator-activated receptor (PPAR){alpha} is a constitutive transcriptional corepressor and inhibits signaling through all PPAR isoforms.

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    Endocrinology. 2005 Apr;146(4):1871-82. Epub 2005 Jan 20.

    Semple RK, Meirhaeghe A, Vidal-Puig AJ, Schwabe JW, Wiggins D, Gibbons GF, Gurnell M, Chatterjee VK, O’Rahilly S.

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    PMID: 15661858 [PubMed – indexed for MEDLINE]

  174. Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidation.

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    Int J Obes Relat Metab Disord. 2004 Dec;28 Suppl 4:S22-8.

    Lelliott C, Vidal-Puig AJ.

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    PMID: 15592482 [PubMed – indexed for MEDLINE]

  175. ETO/MTG8 is an inhibitor of C/EBPbeta activity and a regulator of early adipogenesis.

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    Mol Cell Biol. 2004 Nov;24(22):9863-72.

    Rochford JJ, Semple RK, Laudes M, Boyle KB, Christodoulides C, Mulligan C, Lelliott CJ, Schinner S, Hadaschik D, Mahadevan M, Sethi JK, Vidal-Puig A, O’Rahilly S.

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    PMID: 15509789 [PubMed – indexed for MEDLINE] PMCID: PMC525461

  176. Thyroid hormones directly activate the expression of the human and mouse uncoupling protein-3 genes through a thyroid response element in the proximal promoter region.

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    Biochem J. 2005 Mar 15;386(Pt 3):505-13.

    Solanes G, Pedraza N, Calvo V, Vidal-Puig A, Lowell BB, Villarroya F.

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    PMID: 15496137 [PubMed – indexed for MEDLINE] PMCID: PMC1134869

  177. Nuclear receptor corepressor RIP140 regulates fat accumulation.

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    Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8437-42. Epub 2004 May 20.

    Leonardsson G, Steel JH, Christian M, Pocock V, Milligan S, Bell J, So PW, Medina-Gomez G, Vidal-Puig A, White R, Parker MG.

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    PMID: 15155905 [PubMed – indexed for MEDLINE] PMCID: PMC420412

  178. Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes.

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    Diabetes. 2004 Mar;53(3):842-6.

    Laudes M, Barroso I, Luan J, Soos MA, Yeo G, Meirhaeghe A, Logie L, Vidal-Puig A, Schafer AJ, Wareham NJ, O’Rahilly S.

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    PMID: 14988272 [PubMed – indexed for MEDLINE]

  179. Signalling activity of beta-catenin targeted to different subcellular compartments.

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    Biochem J. 2004 Apr 15;379(Pt 2):471-7.

    Hagen T, Sethi JK, Foxwell N, Vidal-Puig A.

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    PMID: 14733614 [PubMed – indexed for MEDLINE] PMCID: PMC1224088

  180. Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis.

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    J Biol Chem. 2004 Mar 19;279(12):11711-8. Epub 2003 Dec 30.

    Laudes M, Christodoulides C, Sewter C, Rochford JJ, Considine RV, Sethi JK, Vidal-Puig A, O’Rahilly S.

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    PMID: 14701838 [PubMed – indexed for MEDLINE]

  181. Expression of the thermogenic nuclear hormone receptor coactivator PGC-1alpha is reduced in the adipose tissue of morbidly obese subjects.

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    Int J Obes Relat Metab Disord. 2004 Jan;28(1):176-9.

    Semple RK, Crowley VC, Sewter CP, Laudes M, Christodoulides C, Considine RV, Vidal-Puig A, O’Rahilly S.

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    PMID: 14557831 [PubMed – indexed for MEDLINE]

  182. A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling.

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    EMBO J. 2003 Aug 15;22(16):4103-10.

    Echtay KS, Esteves TC, Pakay JL, Jekabsons MB, Lambert AJ, Portero-Otín M, Pamplona R, Vidal-Puig AJ, Wang S, Roebuck SJ, Brand MD.

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    PMID: 12912909 [PubMed – indexed for MEDLINE] PMCID: PMC175801

  183. Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo.

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    Biochem J. 2003 Jul 1;373(Pt 1):155-65.

    Meirhaeghe A, Crowley V, Lenaghan C, Lelliott C, Green K, Stewart A, Hart K, Schinner S, Sethi JK, Yeo G, Brand MD, Cortright RN, O’Rahilly S, Montague C, Vidal-Puig AJ.

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    PMID: 12678921 [PubMed – indexed for MEDLINE] PMCID: PMC1223480

  184. Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma.

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    Diabetes. 2003 Apr;52(4):910-7.

    Savage DB, Tan GD, Acerini CL, Jebb SA, Agostini M, Gurnell M, Williams RL, Umpleby AM, Thomas EL, Bell JD, Dixon AK, Dunne F, Boiani R, Cinti S, Vidal-Puig A, Karpe F, Chatterjee VK, O’Rahilly S.

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    PMID: 12663460 [PubMed – indexed for MEDLINE]

  185. Acute endurance exercise increases skeletal muscle uncoupling protein-3 gene expression in untrained but not trained humans.

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    Metabolism. 2003 Feb;52(2):152-8.

    Noland RC, Hickner RC, Jimenez-Linan M, Vidal-Puig A, Zheng D, Dohm GL, Cortright RN.

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    PMID: 12601624 [PubMed – indexed for MEDLINE]

  186. Differential effects of adiposity on peroxisomal proliferator-activated receptor gamma1 and gamma2 messenger ribonucleic acid expression in human adipocytes.

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    J Clin Endocrinol Metab. 2002 Sep;87(9):4203-7.

    Sewter C, Blows F, Considine R, Vidal-Puig A, O’Rahilly S.

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    PMID: 12213872 [PubMed – indexed for MEDLINE]

  187. Digenic inheritance of severe insulin resistance in a human pedigree.

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    Nat Genet. 2002 Aug;31(4):379-84. Epub 2002 Jul 15.

    Savage DB, Agostini M, Barroso I, Gurnell M, Luan J, Meirhaeghe A, Harding AH, Ihrke G, Rajanayagam O, Soos MA, George S, Berger D, Thomas EL, Bell JD, Meeran K, Ross RJ, Vidal-Puig A, Wareham NJ, O’Rahilly S, Chatterjee VK, Schafer AJ.

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    PMID: 12118251 [PubMed – indexed for MEDLINE]

  188. PPARgamma and the thiazolidinediones: molecular basis for a treatment of ‘Syndrome X’?

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    Diabetes Obes Metab. 2002 Jul;4(4):239-48.

    Sewter C, Vidal-Puig A.

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    PMID: 12099972 [PubMed – indexed for MEDLINE]

  189. Isomer-dependent metabolic effects of conjugated linoleic acid: insights from molecular markers sterol regulatory element-binding protein-1c and LXRalpha.

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    Diabetes. 2002 Jul;51(7):2037-44.

    Roche HM, Noone E, Sewter C, Mc Bennett S, Savage D, Gibney MJ, O’Rahilly S, Vidal-Puig AJ.

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    PMID: 12086931 [PubMed – indexed for MEDLINE]

  190. Characterisation of the phosphorylation of beta-catenin at the GSK-3 priming site Ser45.

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    Biochem Biophys Res Commun. 2002 Jun 7;294(2):324-8.

    Hagen T, Vidal-Puig A.

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    PMID: 12051714 [PubMed – indexed for MEDLINE]

  191. Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-alpha.

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    Diabetes. 2002 Apr;51(4):1035-41.

    Sewter C, Berger D, Considine RV, Medina G, Rochford J, Ciaraldi T, Henry R, Dohm L, Flier JS, O’Rahilly S, Vidal-Puig AJ.

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    PMID: 11916923 [PubMed – indexed for MEDLINE]

  192. Regional differences in the response of human pre-adipocytes to PPARgamma and RXRalpha agonists.

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    Diabetes. 2002 Mar;51(3):718-23.

    Sewter CP, Blows F, Vidal-Puig A, O’Rahilly S.

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    PMID: 11872672 [PubMed – indexed for MEDLINE]

  193. Mitochondrial uncoupling proteins in human physiology and disease.

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    Minerva Med. 2002 Feb;93(1):41-57.

    Hagen T, Vidal-Puig A.

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    PMID: 11850613 [PubMed – indexed for MEDLINE]

  194. Lamin expression in human adipose cells in relation to anatomical site and differentiation state.

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    J Clin Endocrinol Metab. 2002 Feb;87(2):728-34.

    Lelliott CJ, Logie L, Sewter CP, Berger D, Jani P, Blows F, O’Rahilly S, Vidal-Puig A.

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    PMID: 11836312 [PubMed – indexed for MEDLINE]

  195. Resistin: a new link between obesity and insulin resistance?

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    Clin Endocrinol (Oxf). 2001 Oct;55(4):437-8.

    Vidal-Puig A, O’Rahilly S.

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    PMID: 11678824 [PubMed – indexed for MEDLINE]

  196. Resistin / Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans.

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    Diabetes. 2001 Oct;50(10):2199-202.

    Savage DB, Sewter CP, Klenk ES, Segal DG, Vidal-Puig A, Considine RV, O’Rahilly S.

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    PMID: 11574398 [PubMed – indexed for MEDLINE]

  197. Metabolism. Controlling the glucose factory.

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    Nature. 2001 Sep 13;413(6852):125-6.

    Vidal-Puig A, O’Rahilly S.

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    PMID: 11557965 [PubMed – indexed for MEDLINE]

  198. Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

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    Cell. 2001 Jun 15;105(6):745-55.

    Zhang CY, Baffy G, Perret P, Krauss S, Peroni O, Grujic D, Hagen T, Vidal-Puig AJ, Boss O, Kim YB, Zheng XX, Wheeler MB, Shulman GI, Chan CB, Lowell BB.

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    PMID: 11440717 [PubMed – indexed for MEDLINE]

  199. Mitochondrial uncoupling proteins (UCPs) and obesity.

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    Nutr Metab Cardiovasc Dis. 2001 Feb;11(1):70-5.

    Crowley V, Vidal-Puig AJ.

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    PMID: 11383327 [PubMed – indexed for MEDLINE]

  200. Uncoupling protein 3 (UCP3) stimulates glucose uptake in muscle cells through a phosphoinositide 3-kinase-dependent mechanism.

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    J Biol Chem. 2001 Apr 20;276(16):12520-9. Epub 2001 Jan 12.

    Huppertz C, Fischer BM, Kim YB, Kotani K, Vidal-Puig A, Slieker LJ, Sloop KW, Lowell BB, Kahn BB.

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    PMID: 11278970 [PubMed – indexed for MEDLINE]

  201. In vivo effects of uncoupling protein-3 gene disruption on mitochondrial energy metabolism.

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    J Biol Chem. 2001 Jun 8;276(23):20240-4. Epub 2001 Mar 27.

    Cline GW, Vidal-Puig AJ, Dufour S, Cadman KS, Lowell BB, Shulman GI.

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    PMID: 11274222 [PubMed – indexed for MEDLINE]

  202. Uncoupling expectations.

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    Nat Genet. 2000 Dec;26(4):387-8.

    Vidal-Puig AJ.

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    PMID: 11101825 [PubMed – indexed for MEDLINE]

  203. Obesity and diabetes: an avalanche of new information.

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    Mol Med Today. 2000 Jun;6(6):221-3.

    Vidal-Puig A, O’Rahilly S.

    PMID: 10939842 [PubMed – indexed for MEDLINE]

  204. Energy metabolism in uncoupling protein 3 gene knockout mice.

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    J Biol Chem. 2000 May 26;275(21):16258-66.

    Vidal-Puig AJ, Grujic D, Zhang CY, Hagen T, Boss O, Ido Y, Szczepanik A, Wade J, Mootha V, Cortright R, Muoio DM, Lowell BB.

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    PMID: 10748196 [PubMed – indexed for MEDLINE]

  205. Genetic and physiologic analysis of the role of uncoupling protein 3 in human energy homeostasis.

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    Diabetes. 1999 Sep;48(9):1890-5.

    Chung WK, Luke A, Cooper RS, Rotini C, Vidal-Puig A, Rosenbaum M, Chua M, Solanes G, Zheng M, Zhao L, LeDuc C, Eisberg A, Chu F, Murphy E, Schreier M, Aronne L, Caprio S, Kahle B, Gordon D, Leal SM, Goldsmith R, Andreu AL, Bruno C, DiMauro S, Leibel RL, et al.

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    PMID: 10480626 [PubMed – indexed for MEDLINE]

  206. The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis.

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    Int J Obes Relat Metab Disord. 1999 Jun;23 Suppl 6:S49-50.

    Chung WK, Luke A, Cooper RS, Rotini C, Vidal-Puig A, Rosenbaum M, Gordon D, Leal SM, Caprio S, Goldsmith R, Andreu AL, Bruno C, DiMauro S, Heo M, Lowe WL Jr, Lowell BB, Allison DB, Leibel RL.

    Abstractshow

    PMID: 10454123 [PubMed – indexed for MEDLINE]

  207. Role of the beta(3)-adrenergic receptor and/or a putative beta(4)-adrenergic receptor on the expression of uncoupling proteins and peroxisome proliferator-activated receptor-gamma coactivator-1.

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    Biochem Biophys Res Commun. 1999 Aug 11;261(3):870-6.

    Boss O, Bachman E, Vidal-Puig A, Zhang CY, Peroni O, Lowell BB.

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    PMID: 10441518 [PubMed – indexed for MEDLINE]

  208. Effects of obesity and stable weight reduction on UCP2 and UCP3 gene expression in humans.

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    Obes Res. 1999 Mar;7(2):133-40.

    Vidal-Puig A, Rosenbaum M, Considine RC, Leibel RL, Dohm GL, Lowell BB.

    Abstractshow

    PMID: 10102249 [PubMed – indexed for MEDLINE]

  209. Leptin in relation to resumption of menses in women with anorexia nervosa.

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    Mol Psychiatry. 1998 Nov;3(6):544-7.

    Audi L, Mantzoros CS, Vidal-Puig A, Vargas D, Gussinye M, Carrascosa A.

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    PMID: 9857982 [PubMed – indexed for MEDLINE]

  210. Mice expressing human but not murine beta3-adrenergic receptors under the control of human gene regulatory elements.

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    Diabetes. 1998 Sep;47(9):1464-71.

    Ito M, Grujic D, Abel ED, Vidal-Puig A, Susulic VS, Lawitts J, Harper ME, Himms-Hagen J, Strosberg AD, Lowell BB.

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    PMID: 9726236 [PubMed – indexed for MEDLINE]

  211. Troglitazone effects on gene expression in human skeletal muscle of type II diabetes involve up-regulation of peroxisome proliferator-activated receptor-gamma.

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    J Clin Endocrinol Metab. 1998 Aug;83(8):2830-5.

    Park KS, Ciaraldi TP, Lindgren K, Abrams-Carter L, Mudaliar S, Nikoulina SE, Tufari SR, Veerkamp JH, Vidal-Puig A, Henry RR.

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    PMID: 9709955 [PubMed – indexed for MEDLINE]

  212. The human uncoupling protein-3 gene. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts.

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    J Biol Chem. 1997 Oct 10;272(41):25433-6.

    Solanes G, Vidal-Puig A, Grujic D, Flier JS, Lowell BB.

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    PMID: 9325252 [PubMed – indexed for MEDLINE]

  213. Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgamma1 and -2 isoforms and influence of insulin.

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    J Biol Chem. 1997 Aug 8;272(32):20230-5.

    Werman A, Hollenberg A, Solanes G, Bjorbaek C, Vidal-Puig AJ, Flier JS.

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    PMID: 9242701 [PubMed – indexed for MEDLINE]

  214. The organization, promoter analysis, and expression of the human PPARgamma gene.

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    J Biol Chem. 1997 Jul 25;272(30):18779-89.

    Fajas L, Auboeuf D, Raspé E, Schoonjans K, Lefebvre AM, Saladin R, Najib J, Laville M, Fruchart JC, Deeb S, Vidal-Puig A, Flier J, Briggs MR, Staels B, Vidal H, Auwerx J.

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    PMID: 9228052 [PubMed – indexed for MEDLINE]

  215. [Molecular genetics of non insulin dependent diabetes mellitus].

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    Med Clin (Barc). 1997 Jun 14;109(3):107-14.

    Vidal-Puig A, Bjørbaek C.

    PMID: 9289511 [PubMed – indexed for MEDLINE]

  216. UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue.

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    Biochem Biophys Res Commun. 1997 Jun 9;235(1):79-82.

    Vidal-Puig A, Solanes G, Grujic D, Flier JS, Lowell BB.

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    Abstractshow

    PMID: 9196039 [PubMed – indexed for MEDLINE]

  217. Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids.

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    J Clin Invest. 1997 May 15;99(10):2416-22.

    Vidal-Puig AJ, Considine RV, Jimenez-Liñan M, Werman A, Pories WJ, Caro JF, Flier JS.

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    PMID: 9153284 [PubMed – indexed for MEDLINE] PMCID: PMC508081

  218. Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.

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    J Clin Invest. 1996 Jun 1;97(11):2553-61.

    Vidal-Puig A, Jimenez-Liñan M, Lowell BB, Hamann A, Hu E, Spiegelman B, Flier JS, Moller DE.

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    Abstractshow

    PMID: 8647948 [PubMed – indexed for MEDLINE] PMCID: PMC507341

  219. Candidate genes for insulin resistance.

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    Diabetes Care. 1996 Apr;19(4):396-400.

    Moller DE, Bjørbaek C, Vidal-Puig A.

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    PMID: 8729172 [PubMed – indexed for MEDLINE]

  220. Examination of the phosphoenolpyruvate carboxykinase gene promoter in patients with noninsulin-dependent diabetes mellitus.

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    J Clin Endocrinol Metab. 1996 Feb;81(2):503-6.

    Ludwig DS, Vidal-Puig A, O’Brien RM, Printz RL, Granner DK, Moller DE, Flier JS.

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    PMID: 8636258 [PubMed – indexed for MEDLINE]

  221. Genetic variability in the TNF-alpha promoter is not associated with type II diabetes mellitus (NIDDM).

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    Biochem Biophys Res Commun. 1995 Jun 26;211(3):833-9.

    Hamann A, Mantzoros C, Vidal-Puig A, Flier JS.

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    PMID: 7598712 [PubMed – indexed for MEDLINE]

  222. Analysis of the hexokinase II gene in subjects with insulin resistance and NIDDM and detection of a Gln142–>His substitution.

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    Diabetes. 1995 Mar;44(3):340-6.

    Vidal-Puig A, Printz RL, Stratton IM, Granner DK, Moller DE.

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    PMID: 7883122 [PubMed – indexed for MEDLINE]

  223. Tolerance to peripheral tissue is transient and maintained by tissue-specific class I expression.

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    Transplant Proc. 1994 Dec;26(6):3314-6.

    Vidal-Puig A, Faustman DL.

    PMID: 7998151 [PubMed – indexed for MEDLINE]

  224. Hyperinsulinemia in polycystic ovary syndrome: relationship to clinical and hormonal factors.

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    Clin Investig. 1994 Nov;72(11):853-7.

    Vidal-Puig A, Muñoz-Torres M, Jodar-Gimeno E, García-Calvente C, Lardelli P, Ruiz-Requena ME, Escobar-Jiménez F.

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    PMID: 7894211 [PubMed – indexed for MEDLINE]

  225. Reduction of endogenous, ovarian and adrenal androgens with ketoconazole does not alter insulin response in the polycystic ovary syndrome.

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    J Endocrinol Invest. 1994 Sep;17(8):647-52.

    Vidal-Puig A, Muñoz-Torres M, Garcia-Calvente C, Jodar-Gimeno E, Lardelli P, Ruiz-Requena ME, Escobar-Jiménez F.

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    PMID: 7868804 [PubMed – indexed for MEDLINE]

  226. Comparative sensitivity of alternative single-strand conformation polymorphism (SSCP) methods.

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    Biotechniques. 1994 Sep;17(3):490-2, 494, 496.

    Vidal-Puig A, Moller DE.

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    PMID: 7818902 [PubMed – indexed for MEDLINE]

  227. Ketoconazole therapy: hormonal and clinical effects in non-tumoral hyperandrogenism.

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    Eur J Endocrinol. 1994 Apr;130(4):333-8.

    Vidal-Puig AJ, Muñoz-Torres M, Jódar-Gimeno E, García-Calvente CJ, Lardelli P, Ruiz-Requena ME, Escobar-Jiménez F.

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    PMID: 8162160 [PubMed – indexed for MEDLINE]

  228. [Lipid profile of hyperandrogenic women undergoing treatment with ketoconazole and its relationship with the evolution of the hormone pattern].

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    Med Clin (Barc). 1993 Dec 11;101(20):766-8.

    Vidal-Puig A, Muñoz-Torres M, García Calvente C, Lardelli P, Jódar Gimeno E, Cano M, Ruiz Requena ME, Escobar-Jiménez FE.

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    PMID: 8114536 [PubMed – indexed for MEDLINE]

  229. [Adrenal androgens: traditionally forgotten hormones. Today, of current importance].

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    An Med Interna. 1993 Nov;10(11):559-64.

    Vidal-Puig A, García-Calvente C, Muñoz Torres M.

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    PMID: 8117874 [PubMed – indexed for MEDLINE]

  230. [New trends in the definition and diagnostic criteria of polycystic ovary syndrome].

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    Med Clin (Barc). 1993 Mar 13;100(10):389-93.

    Vidal-Puig A, Muñoz-Torres M, Escobar-Jiménez F.

    PMID: 8474284 [PubMed – indexed for MEDLINE]

  231. Dehydroepiandrosterone sulfate and other possible influencing factors that modulate sex hormone-binding globulin levels in the hirsute patient.

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    J Steroid Biochem Mol Biol. 1992 Jul;42(6):607-11.

    Vidal-Puig A, Muñoz-Torres M, Escobar-Jiménez F, Ruiz Requena ME, Garcia-Calvente C, Torres-Vela E.

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    PMID: 1386249 [PubMed – indexed for MEDLINE]

  232. [Primary hypothyroidism associated with changes in the sella turcica and the hypophyseal function. Description of 5 cases].

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    Rev Clin Esp. 1990 Apr;186(6):274-6.

    Muñoz Torres M, Céspedes Mas S, Díaz de Madrid J, Vidal Puig A, Alvarez Cienfuegos E, Escobar Jiménez F.

    Abstractshow

    PMID: 2392582 [PubMed – indexed for MEDLINE]